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José M. Padrón

  • PhD
  • Associate Professor
  • University of La Laguna - Anchieta Campus
  • 21h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 1655CitationsNumber of citations received by José M.'s publications. Updated daily.

Other IDs

Research interests

Anticancer Drug DiscoveryLead Generation to Candidate Realization

About

At BioLab we perform the biological evaluation of synthetic and natural compounds against a panel of representative human solid tumor cell lines. From this test, we determine if compounds are active and/or interesting to go into depth. We try to shed light on the mechanism of action by studying the effects of the products at a molecular level. Our ultimate goal is to identify the biological target(s) at which the active compound is directed. While the core activities of BioLab remain in this specific topic, in the past recent years we have expanded our capacities. At present, three divisions comprise BioLab, namely Bioevaluation, Synthesis and Computation.

Co-authors (307)

  • Luis Báez
  • Muhamad Faid
  • Gastón Silveira

Publications (5)

  • Derivatives of grindelic acid: from a non-active natural diterpene to synthetic antitumor derivatives.

    • Reta G
    • Chiaramello A
    • García C
    • et al.
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  • New strategy toward the diverted synthesis of oxidized abietane diterpenes via oxidation of 6,7-dehydroferruginol methyl ether with dimethyldioxirane

    • Córdova-Guerrero I
    • Andrés L
    • Leal-Orozco A
    • et al.
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  • Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.

    • Backus H
    • Pinedo H
    • Wouters D
    • et al.
    N/AReaders
    N/ACitations
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  • Selective cell kill of the combination of gemcitabine and cisplatin in multilayered postconfluent tumor cell cultures

    • Padrón J
    • Van Moorsel C
    • Bergman A
    • et al.
    N/AReaders
    N/ACitations
  • Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols

    • Padrón J
    • Martin V
    • Hadjipavlou-Litina D
    • et al.
    N/AReaders
    N/ACitations
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Professional experience

Associate Professor

Universidad de La Laguna - Campus Anchieta

January 2017 - Present

Full time Lecturer

Universidad de La Laguna

July 2011 - January 2017(6 years)

TTO Director

Universidad de La Laguna

April 2013 - June 2015(2 years)

Ramón y Cajal Researcher

Universidad de La Laguna

January 2007 - July 2011(5 years)

Postdoc

Universidad de La Laguna

January 2006 - January 2007(a year)

Postdoc

Nuestra Senora de la Candelaria University Hospital

April 2004 - December 2005(2 years)

Postdoc

DSM Deretil

September 2001 - May 2003(2 years)

Postdoc

DSM Research

September 1998 - September 2001(3 years)

Postdoc

VU medisch centrum School of Medical Sciences

January 1997 - July 1998(2 years)

Education

PhD Pharmacy

Universidad de La Laguna

September 1991 - December 1996(5 years)

BSc Pharmacy

Universidad de La Laguna

September 1986 - July 1991(5 years)