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Kasper Harpsøe

  • MSc Pharm., PhD
  • Senior Computational Chemist
  • University of Copenhagen Department of Drug Design and Pharmacology
  • 12h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 553CitationsNumber of citations received by Kasper's publications. Updated daily.

Research interests

Cys-loop receptorsComputational medicinal chemistryComputational drug designGPCRs

About

Computational drug design on G Protein-Coupled Receptors (GPCRs). GPCR mutagenesis data project on the GPCR database, GPCRdb.org

Co-authors (141)

  • Mohammad SEYEDABADI
  • Alexander Hauser
  • Willem Jespers

Publications (5)

  • 5-HT 2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology

    • Peng Y
    • McCorvy J
    • Harpsøe K
    • et al.
    N/AReaders
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  • Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide

    • Di Giglio M
    • Muttenthaler M
    • Harpsøe K
    • et al.
    N/AReaders
    N/ACitations
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  • GPCRdb in 2018: adding GPCR structure models and ligands

    • Pándy-Szekeres G
    • Munk C
    • Tsonkov T
    • et al.
    N/AReaders
    N/ACitations
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  • Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans -γ-Hydroxycrotonic Acid (T-HCA) Analogs

    • Krall J
    • Jensen C
    • Bavo F
    • et al.
    N/AReaders
    N/ACitations
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  • Structural insight to mutation effects uncover a common allosteric site in class C GPCRs

    • Harpsøe K
    • Boesgaard M
    • Munk C
    • et al.
    N/AReaders
    N/ACitations
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Professional experience

Senior Computational Chemist

Kobenhavns Universitet Institut for Lagemiddeldesign og Farmakologi

September 2015 - Present

Postdoc

Kobenhavns Universitet Institut for Lagemiddeldesign og Farmakologi

January 2014 - August 2015(2 years)

Postdoc, Cheminformatics

The Novo Nordisk Foundation Center for Protein Research

March 2012 - December 2013(2 years)

Postdoc

University of Copenhagen, Faculty of Pharmaceutical Sciences

November 2011 - February 2012(3 months)

Postdoc

University of Copenhagen, Faculty of Pharmaceutical Sciences

December 2007 - June 2011(4 years)

Scientific Assistant

University of Copenhagen, Faculty of Pharmaceutical Sciences

October 2007 - November 2007(a month)

Postdoc

University of Copenhagen, Faculty of Pharmaceutical Sciences

July 2007 - September 2007(2 months)

Research Scientist

Arpida A/S

July 2006 - June 2007(a year)

Clinical Research Associate

Quintiles AB

February 2002 - April 2003(a year)

Pharmacist (Temp. in Dept. of Clinical Trials)

Danish Medicines Agency

November 2001 - January 2002(2 months)

Education

PhD in Computational Chemistry

The Danish University of Pharmaceutical Sciences

May 2003 - August 2006(3 years)

MSc in Pharmaceutical Sciences

The Royal Danish School of Pharmacy

September 1995 - July 2001(6 years)