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Maria Blanco-Prieto

  • University of Navarra
  • 31h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 2556CitationsNumber of citations received by Maria's publications. Updated daily.

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About

My research lay in the field of biomaterials and advanced drug carrier systems including the design and the development of polymer and lipid based micro- and nanoscale carriers, their biological evaluation in in vitro cell cultures (toxicity, mechanism of action, intracellular drug release) and also their pharmacokinetic and dynamic impact in vivo (using relevant animal models of the diseases). These micro and nanosystems are prepared using non-toxic, biocompatible and biodegradable biomaterials. Research carried out in this field is mainly applied to cancer, infectious, cardiovascular and neurodegenerative diseases. The main objectives are to target the molecules to their site of action (i.e. cancer cells), to decreases the toxicity of anticancer drugs, to improve the oral absorption of poorly absorbed drugs, to protect fragile molecules like cytokines (for cardiac tissue regeneration) or neurotrophic factors (for brain tissue regeneration) from degradation in the body and to achieve a controlled and sustained release of the entrapped molecules over the time.

Co-authors (230)

  • Nurul Akmarina Mohd Abdul Kamal
  • Elisa Garbayo
  • Edurne Luque

Publications (5)

  • Breaching barriers in glioblastoma. Part I: Molecular pathways and novel treatment approaches.

    • Miranda A, Blanco-Prieto MJ, Sousa J, Pais A V
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  • Breaching barriers in glioblastoma. Part II: Targeted drug delivery and lipid nanoparticles

    • Miranda A
    • Blanco-Prieto M
    • Sousa J
    • et al.
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  • Effectiveness of nanoencapsulated methotrexate against osteosarcoma cells: in vitro cytotoxicity under dynamic conditions.

    • Mitxelena-Iribarren O, Hisey CL, Errazquin-Irigoyen M, González-Fernández Y, Imbuluzqueta E, Mujika M,Blanco-Prieto MJ A
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  • Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord

    • Des Rieux A
    • De Berdt P
    • Ansorena E
    • et al.
    N/AReaders
    13Citations
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  • Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia

    • Vilas-Zornoza A
    • Agirre X
    • Abizanda G
    • et al.
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    17Citations
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Education history

Professor

Universidad de Navarra

April 1999 - Present

Post-doctoral fellow

Swiss Federal Institute of Technology Zurich Department of Health Sciences and Technology

April 1996 - March 1999(3 years)

Master and PhD

Université Paris Sud

October 1991 - March 1996(4 years)

Pharmacy

Universidade de Santiago de Compostela

September 1986 - June 1991(5 years)