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Mark van der Giezen

  • PhD
  • Associate Professor of Evolutionary Biochemistry
  • University of Exeter
  • 27h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 3266CitationsNumber of citations received by Mark's publications. Updated daily.

Recent publications

  • New genotyping method for the causative agent of crayfish plague (Aphanomyces astaci) based on whole genome data

    • Minardi D
    • Studholme D
    • van der Giezen M
    • et al.
    N/AReaders
    2Citations
    Get full text
  • Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans

    • Vanhatalo A
    • Blackwell J
    • L'Heureux J
    • et al.
    N/AReaders
    14Citations
    Get full text

Professional experience

Associate Professor of Evolutionary Biochemistry

University of Exeter

January 2019 - Present

Senior Lecturer in Evolutionary Biochemistry

University of Exeter

September 2007 - December 2018(11 years)

Lecturer in Microbiology

Queen Mary, University of London

November 2004 - August 2007(3 years)

Postdoctoral Fellow

Royal Holloway University of London

April 2002 - October 2004(3 years)

Postdoctoral Fellow

Natural History Museum, London, UK

October 1997 - March 2002(4 years)

Education

PhD

Rijksuniversiteit Groningen - University of Groningen

December 1992 - September 1997(5 years)

Drs

Rijksuniversiteit Groningen - University of Groningen

September 1988 - November 1992(4 years)

About

How microbes interact with their hosts plays an important role in human and animal health. Especially the microbes in the gut are of crucial importance. We are interested in how these microbes affect human and animal health. Research includes important human and animal pathogens but also focusses on microbes and nutrition and their role in food security. Adaptation of microbial eukaryotes to low oxygen, as found in the gut for example, featured in several high impact publications (Nature (2003) 426, 172-176, Current Biology (2008) 18, 580-585, Current Biology (2014) 24, 1176-1186 and PLoS Biology (2017) 15(9) e2003769) and included major human pathogens such as Giardia intestinalis, Entamoeba histolytica and Blastocystis. We hope that understanding their unusual biochemistry might lead to new drug targets. Food security research focuses at biochemistry and genomics of several important livestock and fisheries pathogens such as Aphanomyces and Fasciola hepatica. Aphanomyces causes two notifyable diseases: crayfish plague (click here for a recent publication) and epizootic ulcerative syndrome in fish while Fasciola causes liver fluke in cattle and sheep. A project with the National Lobster Hatchery and Cefas focuses on the role of the gut microbiome on lobster health. As part of this work, we were the first to describe a new pathogen of European Lobster (see here). Together with colleagues at Sports and Health Sciences and our Medical School we study how fruit and vegetables improve health and cognition as it is becoming increasingly clear microbes in our alimentary tract play crucial roles in health (see for example our involvement in Free Radic. Biol. Med. (2018) 124, 21-30.) Our lab uses a variety of techniques to answer our research questions. Molecular biology, cell biology, biochemistry, bioinformatics and next-generation sequencing methods are routinely used.

Groups

Co-authors (281)