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Maurizio Romano

  • PhD
  • Assistant Professor
  • University of Trieste Department of Life Sciences
  • 17h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 2153CitationsNumber of citations received by Maurizio's publications. Updated daily.

Research interests

hnRNPsmRNASplicingFTLD-UALSNeurodegenerationTARDBPTDP-43

About

Dr. Maurizio Romano is an Assistant Professor at the University of Trieste (Italy). He has studied Biology at the University of Trieste from 1985 to 1990 to obtain a Biology degree with full marks. From 1990 to 1994, he obtained a PhD course in Experimental and Clinical Pathology working in the General Pathology Department of the University of Trieste under the supervision of Prof. Pietro Dri and Pierluigi Patriarca. He was involved in a project aimed at characterizing the genetic and molecular basis of the human leukocyte myeloperoxidase (MPO) and eosinophil peroxidase (EPO) deficiencies. From 1991 to 1995, he moved to the Molecular Pathology Laboratory of ICGEB in Trieste, where he worked under the supervision of the Prof. Francisco Baralle (director of the ICGEB in Trieste), and carried out the genetic screening in order to identify novel mutations in the human MPO and EPO genes and then set up systems to analyze the impact of these mutations on the activity and turn over of leukocite enzymes. After PhD, the scientific interests of Dr. Romano progressively shifted towards the characterization of mechanisms underlying physiologic and pathologic splicing processes (MPO, CFTR, APOA2, THPO, CBS). In 1995, he got the position of Assistant Professor of General Pathology at the University of Trieste and mantained full collaboration (still ongoing) with the laboratories of Molecular Pathology and Biotechnology Development at ICGEB of Trieste . Between 1999 and 2001, as part of a research project on Cystic Fibrosis, he contributed to the identification of the nuclear protein TDP-43 as a potential CFTR exon 9 pre-mRNA splicing regulator. Actually, his research is mainly focused on setting up in vitro and in vivo models and systems to better characterize the pathophysiological mechanisms underlying frontotemporal lobar degeneration (FTLD), amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. Since 1995, he has been teached General Pathology at the Faculty of Medicine in the University of Trieste. Currently, he is teaching Molecular Pathology and Pathophysiology for the Masters Degree in Biotechnology and the Masters Degree in Pharmacy at the University of Trieste.

Co-authors (148)

  • Emanuele Buratti

Publications (5)

  • Essential role of hippocampal noradrenaline in the regulation of spatial working memory and TDP-43 tissue pathology

    • Pintus R
    • Riggi M
    • Cannarozzo C
    • et al.
    N/AReaders
    0Citations
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  • RhoGAPp190: A potential player in tbph-mediated neurodegeneration in Drosophila

    • Langellotti S
    • Romano G
    • Feiguin F
    • et al.
    N/AReaders
    0Citations
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  • Glycolipid analysis of different tissues and cerebrospinal fluid in type II Gaucher disease

    • Gornati R
    • Berra B
    • Montorfano G
    • et al.
    N/AReaders
    N/ACitations
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  • Minor role for BRCA2 (exon11) and p53 (exon 5-9) among Sudanese breast cancer patients

    • Masri M
    • Abdel Seed N
    • Fahal A
    • et al.
    N/AReaders
    N/ACitations
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  • Effect of biological surfaces on neutrophil O2 - production and its relationship to the CD11b/CD18 integrin-dependent adherence

    • Dri P
    • Cramer R
    • Romano M
    • et al.
    N/AReaders
    N/ACitations

Editorships

BMC Molecular Biology

Associate Editor

2016 - Present

Professional experience

Assistant Professor

Universita degli Studi di Trieste Dipartimento di Scienze della Vita

July 1995 - Present

Education

PhD

Universita degli Studi di Trieste

January 1991 - December 1994(4 years)

Master's Degree in Biology

Universita degli Studi di Trieste

October 1985 - July 1990(5 years)