At the proteomics’ time, mass spectrometry appears to be a powerful tool to find and identify peptides and proteins from purified sample. A new era is now beginning, with the MALDI imaging, allowing both research, identification while conserving the localization of biomolecules like peptides, proteins and lipids in tissues. Crucial developments at the level of the sample preparations are in progress to improve the performances of this technology.
Spatially-Resolved Top-down Proteomics Bridged to MALDI MS Imaging Reveals the Molecular Physiome of Brain Regions
Erratum: A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits (PLoS ONE (2013) 8:1 DOI: 10.1371/annotation/ b97d3c0d-b49e-40e3-a6b4-5155bd9