Skip to content

Michael Hoffman

  • PhD
  • Assistant Professor
  • University of Toronto Department of Medical Biophysics
--

Readers

Number of times these publications have been added to libraries on Mendeley.
15

Publications

Number of items in this person’s My Publications folder on Mendeley.

Research Interests

functional genomics machine learning chromatin

Followers (8)

  • Tobias Sikosek

    Tobias Sikosek University of Toronto, Department of Biochemistry, Hue Sun Chan's lab

  • Rene Welch

    Rene Welch University of Wisconsin Madison Graduate School

  • Coby Viner

    Coby Viner University of Toronto

  • William Noble

    William Noble

  • Paul Ellenbogen

    Paul Ellenbogen

Explore network

Following (6)

Explore network

About

I develop machine learning methods for functional genomics. I am responsible for Segway, a dynamic Bayesian network method for simultaneously segmenting and clustering multiple tracks of data from ChIP-seq or DNase-seq experiments.

Publications

Joint annotation of chromatin state and chromatin conformation reveals relationships among domain types and identifies domains of cell type-specific expression

Libbrecht M, Ay F, Hoffman M, Gilbert D, Bilmes J, Noble W

Genome Research (2015)

  • Get full text at journal
  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Statistical Inference , Learning and Models in Big Data

Franke B, Plante J, Roscher R, Lee A, Smyth C, Hatefi A, Chen F, Gil E, Schwing A, Selvitella A, Hoffman M, Grosse R, Hendricks D, Reid N

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Comparative analysis of metazoan chromatin organization

Ho J, Jung Y, Liu T, Alver B, Lee S, Ikegami K, Sohn K, Minoda A, Tolstorukov M, Appert A, Parker S, Gu T, Kundaje A, Riddle N, Bishop E, Egelhofer T, Hu S, Alekseyenko A, Rechtsteiner A, Asker D, Belsky J, Bowman S, Chen Q, Chen R, Day D, Dong Y, Dose A, Duan X, Epstein C, Ercan S, Feingold E, Ferrari F, Garrigues J, Gehlenborg N, Good P, Haseley P, He D, Herrmann M, Hoffman M, Jeffers T, Kharchenko P, Kolasinska-Zwierz P, Kotwaliwale C, Kumar N, Langley S, Larschan E, Latorre I, Libbrecht M, Lin X, Park R, Pazin M, Pham H, Plachetka A, Qin B, Schwartz Y, Shoresh N, Stempor P, Vielle A, Wang C, Whittle C, Xue H, Kingston R, Kim J, Bernstein B, Dernburg A, Pirrotta V, Kuroda M, Noble W, Tullius T, Kellis M, MacAlpine D, Strome S, Elgin S, Liu X, Lieb J, Ahringer J, Karpen G, Park P

Nature (2014)

  • Get full text at journal
  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Integrative annotation of chromatin elements from ENCODE data.

Hoffman M, Ernst J, Wilder S, Kundaje A, Harris R, Libbrecht M, Giardine B, Ellenbogen P, Bilmes J, Birney E, Hardison R, Dunham I, Kellis M, Noble W

Nucleic Acids Research (2013)

  • Get full text at journal
  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

An integrated encyclopedia of DNA elements in the human genome.

Bernstein B, Birney E, Dunham I, Green E, Gunter C, Snyder M

Nature (2012)

  • Get full text at journal
  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Professional experience

Assistant Professor

University of Toronto Department of Medical Biophysics

April 2014 - Present

Scientist

Princess Margaret Hospital Cancer Centre

November 2013 - Present

Senior Fellow

University of Washington Department of Genome Sciences

September 2008 - October 2013 (5 years 1 month)

Predoctoral Fellow

European Bioinformatics Institute

October 2003 - July 2008 (4 years 9 months)

Research Assistant

Department of Chemistry and Biochemistry, University of Texas at Austin

May 1999 - September 2003 (4 years 4 months)

Education history

University of Cambridge Trinity College

Doctor of Philosophy

October 2003 - July 2008 (4 years 9 months)

University of Texas at Austin

Bachelor of Science, Biochemistry; Bachelor of Arts, Plan II Honors Liberal Arts

August 1998 - May 2003 (4 years 9 months)