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Michael Przewosny

  • PhD
  • Head of laboratory
  • Grünenthal GmbH
  • 0ReadersNumber of instances of Michael's publications in Mendeley libraries. Updated daily.
  • 33PublicationsNumber of items in Michael's My Publications folder on Mendeley.

Research interests

impuritmulti component reactionsreaction mechanismmolecular modellinglaboratory automationchromatographyspectroscopyparallel synthesissolid phase synthesisinflammationpainanalgesicsmedicinal chemistryorganometallicsheterocycles

About

Professional Career 12/1997 – present Laboratory Head with Gruenenthal GmbH, Aachen, Germany Main tasks: guidance of 2 – 6 laboratory technicians in synthetic, analytical and preparative chromatography laboratories; development of methods to build combinatorial libraries, design of building blocks for focused libraries, development of hit-to-lead strategies, involved in target assessments, synthetic strategies for preclinical medicinal, lead structure optimization, chemical development, metabolite synthesis, route finding, analytical and preparative chromatography projects; project work within these projects; management of (international) analytical and medicinal chemistry, scale-up & development CRO projects; CMC management; patent management; scientific and analytical data management; management of scientific consultancy, examination of competitive intelligence. 1993 – 1997 Various position as scientific assistant at German Wool Research Center at the RWTH Aachen e.V. Main tasks: contract synthesis for companies, e.g. photo affinity labels (Boehringer Penzdorf, Germany), hair dyes (Procter & Gamble, UK), peptides and peptide mimetics (Hannover Medical School, Germany). Education 11/1993 Ph.D. as „Dr. rer. nat.” in Macromolecular Chemistry (thesis on synthesis of backbone-modified C3a analogues using new methods for coupling and derivatization), German Wool Research Center at the RWTH Aachen e.V. 1990 – 1993 Ph.D., German Wool Research Center at the RWTH Aachen e.V. 1981 – 1990 Study of Chemistry, B.Sc./M.Sc., RWTH Aachen, Germany 1980 – 1981 Study of Metallurgy, RWTH Aachen, Germany 1979 – 1980 Military Service, Airforce, Budel, The Netherlands, and Kalkar, Germany 1979 „Abitur“ at Krupp Gymnasium, Duisburg-Rheinhausen, Germany

Publications (5)

  • Substituierte 1,3-Dioxoisoindoline als Arzneimittel

    • Przewosny M
    N/AReaders
    N/ACitations
  • Substituierte aromatische Diamine als Liganden der vesikulären Glutamat-Transporter 1 und 2 (vGLUT1 und vGLUT2)

    • Przewosny M
    • Bahrenberg G
    • Kless A
    • et al.
    N/AReaders
    N/ACitations
  • Substituierte aromatische Dicarbonsäureamide als Arzneimittel

    • Przewosny M
    • Bahrenberg G
    • Kless A
    • et al.
    N/AReaders
    N/ACitations
  • Synthesis and properties of C-terminal C3A analogs with methyleneamino bonds

    • Przewosny M
    • Bitter-Suermann D
    • Höcker H
    N/AReaders
    N/ACitations
  • Synthesis and properties of C-terminal C3A analogs with methyleneamino bonds

    • Przewosny M
    • Bitter-Suermann D
    • Höcker H
    N/AReaders
    N/ACitations

Professional experience

Head of laboratory

Grünenthal GmbH

December 1997 - Present

Education history

Deutsches Wollforschungsinstitut an der RWTH Aachen

December 1993 - November 1997(4 years)

PhD

Deutsches Wollforschungsinstitut an der RWTH Aachen

May 1990 - November 1993(4 years)

Diploma

RWTH Aachen

October 1980 - April 1990(10 years)