Morgan Langille PhD

Assistant Professor

Dalhousie University

Location
Halifax, Canada
Discipline
Biological Sciences
Interests
Human microbiome, metagenomics, evolution, phylogenetic diversity
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About

I was raised in a small town in New Brunswick, Canada and completed concurrent Science and Computer Science Bachelor's degrees at University of New Brunswick. My first taste of research was identifying retro-transposed genes in Drosophila melanogaster using bioinformatics. I then moved to Vancouver, BC to complete my PhD in identifying genomic islands in Bacteria and Archaea genomes under the supervision of Dr. Fiona Brinkman. My first post-doc for 2 years was with Dr. Jonathan Eisen at UC Davis working with the iSEEM group to develop better computational methods to analyze metagenomic datasets from the ocean. My second post-doc brought me back to the east coast at Dalhousie University in Halifax, N.S., Canada working with Dr. Rob Beiko and Dr. Ford Doolittle on the human microbiome. This led to the development of PICRUSt, a bioinformatics method to predict metagenomes from 16S surveys. I am now an Assistant Professor in the Department of Pharmacology at Dalhousie University studying human microbial interactions and their impact on health.
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Publications

Microbial shifts in the aging mouse gut

Langille M, Meehan C, Koenig J, Dhanani A, Rose R, Howlett S et al.

Microbiome (2014)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

IslandViewer 3: more flexible, interactive genomic island discovery, visualization and analysis

Dhillon B, Laird M, Shay J, Winsor G, Lo R, Nizam F et al.

Nucleic Acids Research (2015)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups.

Hester C, Jala V, Langille M, Umar S, Greiner K, Haribabu B

World journal of gastroenterology : WJG (2015)

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Which is more important for classifying microbial communities: who's there or what they can do?

Xu Z, Malmer D, Langille M, Way S, Knight R

The ISME journal (2014)

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Interactions in the microbiome: communities of organisms and communities of genes.

Boon E, Meehan C, Whidden C, Wong D, Langille M, Beiko R

FEMS microbiology reviews (2014)

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Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences.

Langille M, Zaneveld J, Caporaso J, McDonald D, Knights D, Reyes J et al.

Nature biotechnology (2013)

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GenGIS 2: geospatial analysis of traditional and genetic biodiversity, with new gradient algorithms and an extensible plugin framework.

Parks D, Mankowski T, Zangooei S, Porter M, Armanini D, Baird D et al.

PloS one (2013)

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IslandViewer update: Improved genomic island discovery and visualization.

Dhillon B, Chiu T, Laird M, Langille M, Brinkman F

Nucleic acids research (2013)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Functional Biogeography of Ocean Microbes Revealed through Non-Negative Matrix Factorization.

Jiang X, Langille M, Neches R, Elliot M, Levin S, Eisen J et al.

PloS one (2012)

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Sifting through genomes with iterative-sequence clustering produces a large, phylogenetically diverse protein-family resource.

Sharpton T, Jospin G, Wu D, Langille M, Pollard K, Eisen J

BMC bioinformatics (2012)

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Sequencing of seven haloarchaeal genomes reveals patterns of genomic flux.

Lynch E, Langille M, Darling A, Wilbanks E, Haltiner C, Shao K et al.

PloS one (2012)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

MicrobeDB: a locally maintainable database of microbial genomic sequences.

Langille M, Laird M, Hsiao W, Chiu T, Eisen J, Brinkman F

Bioinformatics (2012)

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Human microbiome: a genetic bazaar for microbes?

Langille M, Meehan C, Beiko R

Current biology : CB (2012)

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Detecting genomic islands using bioinformatics approaches

Langille M, Hsiao W, Brinkman F

Nature Reviews Microbiology (2010)

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BioTorrents: A File Sharing Service for Scientific Data

Langille M, Eisen J

PLoS ONE (2010)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Parent genes of retrotransposition-generated gene duplicates in Drosophila melanogaster have distinct expression profiles.

Langille M, Clark D

Genomics (2007)

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The association of virulence factors with genomic islands.

Ho Sui S, Fedynak A, Hsiao W, Langille M, Brinkman F

PloS one (2009)

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Color lesion boundary detection using live wire

Chodorowski A, Mattsson U, Langille M, Hamarnehc G

Proceedings of SPIE (2005)

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3D live-wire-based semi-automatic segmentation of medical images

Hamarneh G, Yang J, McIntosh C, Langille M

Proceedings of SPIE (2005)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Data Standards for Flow Cytometry

Spidlen J, Gentleman R, Haaland P, Langille M, Meur N, Ochs M et al.

OMICS (2006)

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Bioinformatic detection of horizontally transferred DNA in bacterial genomes

Langille M, Brinkman F

F1000 Biology Reports (2009)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa.

Winstanley C, Langille M, Fothergill J, Kukavica-Ibrulj I, Paradis-Bleau C, Sanschagrin F et al.

Genome research (2009)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Computational prediction and characterization of genomic islands: insights into bacterial pathogenicity

Langille M

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

IslandViewer: an integrated interface for computational identification and visualization of genomic islands.

Langille M, Brinkman F

Bioinformatics (2009)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Evaluation of genomic island predictors using a comparative genomics approach.

Langille M, Hsiao W, Brinkman F

BMC bioinformatics (2008)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Mobile genetic elements and their prediction

Langille M, Zhou F, Fedynak A, Hsiao W, Xu Y, Brinkman F

Computational Methods for Understanding Bacterial and Archaeal Genomes (2008)

  • -- Readers Readers not available. This publication is not currently accessible in the Mendeley catalog.

Professional experience

Assistant Professor

Dalhousie University

January 2014 - Present

Post doc

Dalhousie University

May 2011 - December 2013 (2 years 7 months)

Post-Doc

UC Davis

May 2009 - April 2011 (1 year 11 months)

Education history

Simon Fraser University

PhD

September 2004 - April 2009 (4 years 7 months)

University of New Brunswick

BSc (Biology) & BCS

September 1999 - April 2004 (4 years 7 months)