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Paul Jaschke

  • PhD
  • Lecturer (Assistant Professor)
  • Macquarie University
  • --

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  • 9

    Publications

    Number of items in this person’s My Publications folder on Mendeley.

Research Interests

Bacteriophage Genome design and assembly Bioengineering synthetic biology

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About

I am now a Lecturer (equivalent of Assistant Professor) of Synthetic Biology in the Department of Chemistry and Biomolecular Sciences at Macquarie University in Sydney, Australia. I started off my science career at the University of Alberta (Canada), working in the Casey and Michalak labs. Summer student work in the Casey Lab on the human sodium-bicarbonate co-transporter protein resulted in an authorship in a peer-reviewed publication. My honors project in the Michalak Lab had me determining the role of calcium signaling and calreticulin on murine embryonic stem cell differentiation. After achieving a B.Sc. (Honors) in Biochemistry in 2003 I went to the Beatty Lab at the University of British Columbia to start my Ph.D. While at UBC I discovered that a photosynthetic organism called Rhodobacter sphaeroides was capable of re-routing its chlorophyll biosynthetic machinery around a blockage to generate a new type of chlorophyll. November 2010 I was conferred a Ph.D in Microbiology and Immunology from UBC. I was a post-doc in Drew Endy's lab at Stanford University from Nov 2010 - June 2015. The focus of my project was on redesign phage using both rational and combinatorial methods in order to finish the genetics of a simple system.

Publications

A fully decompressed synthetic bacteriophage øX174 genome assembled and archived in yeast.

  • Jaschke P
  • Lieberman E
  • Rodriguez J
  • Sierra A
  • Endy D
Virology (2012)
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Electron transfer in Rhodobacter sphaeroides reaction centers containing Zn-bacteriochlorophylls: a hole-burning study.

  • Neupane B
  • Jaschke P
  • Saer R
  • Beatty J
  • Reppert M
  • Jankowiak R
The journal of physical chemistry. B (2012)
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A bchD (magnesium chelatase) mutant of Rhodobacter sphaeroides synthesizes zinc bacteriochlorophyll through novel zinc-containing intermediates.

  • Jaschke P
  • Hardjasa A
  • Digby E
  • Hunter C
  • Beatty J
The Journal of Biological Chemistry (2011)
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The PucC protein of Rhodobacter capsulatus mitigates an inhibitory effect of light-harvesting 2 alpha and beta proteins on light-harvesting complex 1.

  • Jaschke P
  • Leblanc H
  • Lang A
  • Beatty J
Photosynthesis research (2008)
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The photosystem of Rhodobacter sphaeroides assembles with zinc bacteriochlorophyll in a bchD (magnesium chelatase) mutant.

  • Jaschke P
  • Beatty J
Biochemistry (2007)
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Professional experience

Lecturer (Assistant Professor)

Macquarie University

October 2015

Post-doctoral Researcher

Stanford University Department of Bioengineering

November 2010 - June 2015 (5 years)

Research Technician

Department of Chemistry, University of Queensland

May 2004 - July 2004 (2 months)

Education history

University of British Columbia Department of Microbiology and Immunology

Ph.D.

September 2004 - August 2010 (6 years)

University of Alberta Department of Biochemistry

B.Sc.

September 1999 - June 2003 (4 years)