Towards the computational design of protein post-translational regulation
Bioorganic & Medicinal Chemistry (2015)
Differential genetic interactions of yeast stress response MAPK pathways
Molecular Systems Biology (2015)
Phosphoproteomic Analysis Reveals Regulatory Mechanisms at the Kidney Filtration Barrier.
Journal of the American Society of Nephrology : JASN (2014)
Evolution and functional cross-talk of protein post-translational modifications.
Molecular systems biology (2013)
Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
Nature methods (2013)
Hierarchical Modularity and the Evolution of Genetic Interactomes across Species.
Molecular cell (2012)
Comparative interaction networks: bridging genotype to phenotype.
Advances in experimental medicine and biology (2012)
Systematic Functional Prioritization of Protein Posttranslational Modifications
Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress.
Proceedings of the National Academy of Sciences of the United States of America (2011)
Phenotypic landscape of a bacterial cell.
Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action
Molecular Systems Biology (2010)
A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.
Molecular systems biology (2010)
ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs.
Bioinformatics (Oxford, England) (2009)
Quantitative genetic interactions reveal biological modularity.
Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
PLoS biology (2009)
Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions.
Journal of molecular biology (2009)
Microblogging the ISMB: a new approach to conference reporting.
PLoS computational biology (2009)
Evolvability and hierarchy in rewired bacterial gene networks.
Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.
PLoS computational biology (2008)
Analyzing protein interaction networks using structural information.
Annual review of biochemistry (2008)
Structures in systems biology.
Current opinion in structural biology (2007)
A genome-wide Ras-effector interaction network.
Journal of molecular biology (2007)
Specificity and evolvability in eukaryotic protein interaction networks.
PLoS computational biology (2007)
Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions.
PLoS computational biology (2005)
Comparative evolutionary genomics unveils the molecular mechanism of reassignment of the CTG codon in Candida spp.
Genome research (2003)
SmartCell, a framework to simulate cellular processes that combines stochastic approximation with diffusion and localisation: analysis of simple networks
Systems Biology (2004)
January 2013 - Present
Postdoc in the Krogan and Lim labs
December 2012 - Present
PhD student in the Serrano Lab
European Molecular Biology Laboratory
January 2003 - December 2007 (4 years 11 months)
Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia da Universidade de Coimbra
June 1997 - October 2002 (5 years 4 months)