Pedro Beltrao

  • PhD
  • Researcher
  • Group Leader
  • EMBL-EBI
  • Agricultural and Biological Sciences

Research Interests

Evolution of cellular interactions cell signaling systems and chemical-interactions. Interested in understanding how variation introduced at the level of the DNA gets propagated via structures and interaction networks to have an impact on phenotypes.

Followers (26)

Explore network

Following (24)

  • Colm Ryan

    Colm Ryan University College Dublin

  • Pedro Príncipe

    Pedro Príncipe University of Minho

  • Mafalda Almeida

    Mafalda Almeida

  • Robin Haw

    Robin Haw

  • Conor Lawless

    Conor Lawless Institute for Cellular and Molecular Biosciences, Newcastle University

Explore network

Publications

Differential genetic interactions of yeast stress response MAPK pathways

Martin H, Shales M, Fernandez-Pinar P, Wei P, Molina M, Fiedler D, et al.

Molecular Systems Biology (2015)

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Kinase-two-hybrid: towards the conditional interactome

Ochoa D, Beltrao P

Molecular Systems Biology (2015)

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Towards the computational design of protein post-translational regulation

Strumillo M, Beltrao P

Bioorganic & Medicinal Chemistry (2015)

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Uncovering phosphorylation-based specificities through functional interaction networks.

Wagih O, Sugiyama N, Ishihama Y, Beltrao P

Molecular & cellular proteomics : MCP (2015)

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Phosphoproteomic Analysis Reveals Regulatory Mechanisms at the Kidney Filtration Barrier.

Rinschen M, Wu X, König T, Pisitkun T, Hagmann H, Pahmeyer C, et al.

Journal of the American Society of Nephrology : JASN (2014)

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Evolution and functional cross-talk of protein post-translational modifications.

Beltrao P, Bork P, Krogan N, van Noort V

Molecular systems biology (2013)

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Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.

Swaney D, Beltrao P, Starita L, Guo A, Rush J, Fields S, et al.

Nature methods (2013)

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Comparative interaction networks: bridging genotype to phenotype.

Beltrao P, Ryan C, Krogan N

Advances in experimental medicine and biology (2012)

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Hierarchical Modularity and the Evolution of Genetic Interactomes across Species.

Ryan C, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, et al.

Molecular cell (2012)

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Systematic Functional Prioritization of Protein Posttranslational Modifications

Beltrao P, Albanèse V, Kenner L, Swaney D, Burlingame A, Villén J, et al.

Cell (2012)

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Phenotypic landscape of a bacterial cell.

Nichols R, Sen S, Choo Y, Beltrao P, Zietek M, Chaba R, et al.

Cell (2011)

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Site-specific acetylation mark on an essential chromatin-remodeling complex promotes resistance to replication stress.

Charles G, Chen C, Shih S, Collins S, Beltrao P, Zhang X, et al.

Proceedings of the National Academy of Sciences of the United States of America (2011)

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A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers.

Lefebvre C, Rajbhandari P, Alvarez M, Bandaru P, Lim W, Sato M, et al.

Molecular systems biology (2010)

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Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action

Kapitzky L, Beltrao P, Berens T, Gassner N, Zhou C, Wüster A, et al.

Molecular Systems Biology (2010)

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Quantitative genetic interactions reveal biological modularity.

Beltrao P, Cagney G, Krogan N

Cell (2010)

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ADAN: a database for prediction of protein-protein interaction of modular domains mediated by linear motifs.

Encinar J, Fernandez-Ballester G, Sánchez I, Hurtado-Gomez E, Stricher F, Beltrao P, et al.

Bioinformatics (Oxford, England) (2009)

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Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Beltrao P, Trinidad J, Fiedler D, Roguev A, Lim W, Shokat K, et al.

PLoS biology (2009)

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Microblogging the ISMB: a new approach to conference reporting.

Saunders N, Beltrão P, Jensen L, Jurczak D, Krause R, Kuhn M, et al.

PLoS computational biology (2009)

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Structure-based prediction of the Saccharomyces cerevisiae SH3-ligand interactions.

Fernandez-Ballester G, Beltrao P, Gonzalez J, Song Y, Wilmanns M, Valencia A, et al.

Journal of molecular biology (2009)

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Analyzing protein interaction networks using structural information.

Kiel C, Beltrao P, Serrano L

Annual review of biochemistry (2008)

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Evolvability and hierarchy in rewired bacterial gene networks.

Isalan M, Lemerle C, Michalodimitrakis K, Horn C, Beltrao P, Raineri E, et al.

Nature (2008)

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Genome-wide prediction of SH2 domain targets using structural information and the FoldX algorithm.

Sánchez I, Beltrao P, Stricher F, Schymkowitz J, Ferkinghoff-Borg J, Rousseau F, et al.

PLoS computational biology (2008)

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A genome-wide Ras-effector interaction network.

Kiel C, Foglierini M, Kuemmerer N, Beltrao P, Serrano L

Journal of molecular biology (2007)

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Specificity and evolvability in eukaryotic protein interaction networks.

Beltrao P, Serrano L

PLoS computational biology (2007)

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Structures in systems biology.

Beltrao P, Kiel C, Serrano L

Current opinion in structural biology (2007)

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Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions.

Beltrao P, Serrano L

PLoS computational biology (2005)

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SmartCell, a framework to simulate cellular processes that combines stochastic approximation with diffusion and localisation: analysis of simple networks

Ander M, Beltrao P, Di Ventura B, Ferkinghoff-Borg J, Foglierini M, Lemerle C, et al.

Systems Biology (2004)

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Comparative evolutionary genomics unveils the molecular mechanism of reassignment of the CTG codon in Candida spp.

Massey S, Moura G, Beltrão P, Almeida R, Garey J, Tuite M, et al.

Genome research (2003)

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Professional experience

Group Leader

EMBL-EBI

January 2013 - Present

Postdoc in the Krogan and Lim labs

University of California San Fransisco Division of Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome

December 2012 - Present

PhD student in the Serrano Lab

European Molecular Biology Laboratory

January 2003 - December 2007 (4 years 11 months)

Education history

Departamento de Ciências da Vida, Faculdade de Ciências e Tecnologia da Universidade de Coimbra

Biochemistry

June 1997 - October 2002 (5 years 4 months)