Tuberculosis epidemiologyHuman models in DrosophilaMathematical modellingImmunopathologyTuberculosis
I’ve been studying TB from an immunopathogenic point of view, using experimental modelling “in vitro”, “in vivo” and “in silico”, as well as using tissues from human origin. I’ve authored different hypothesis to explain it; “Dynamic hypothesis”; “Citadel Paradox”; “Confluent hypothesis”. On 2000 we developed the first therapeutic vaccine against tuberculosis RUTI®, developed by Archivel Farma which has successfully finished a Phase II Clinical trial. Now I’m the leader of MANREMYC (http://www.manremyc.cat), a spin off to develop the first supplement food against TB, based on heat-killed Mycobacterium manresensis, to reduce the risk of suffering TB. Fortunately this will be easily disseminated and will become a definitive tool to control this terrible disease !