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Prateek Joshi

  • Masters
  • Ph.D Student
  • IIT - Italian Institute of Technology, RBCS - Robotics, Brain and Cognitive Sciences Department
  • 1PublicationsNumber of items in Prateek's My Publications folder on Mendeley.

Research interests

Regenerative Medicine and Tissue Engineering

About

Something about my past experience. After earning my master’s degree, I joined the research laboratory at IGIB from February 2008 to March 2010 as a research assistant. During this period I worked on elucidating genes important in developmental processes by injecting gene breaking trap vectors and screening for visible developmental phenotypes using confocal microscopy. I was also involved in the building databases like FishMap and Zebrafish GenomeWiki. Additionally, I was a core member of fish room staff and used to take care of day to day working of the fish room. Our team, for the first time in the world, sequenced the wild type strain of the zebrafish and generated over 89 Gigabases of DNA sequences in two months time resulting in over 20X coverage of the Zebrafish genome.For my Master’s dissertation project, I chose to study the process of vasculogenesis and angiogenesis in zebrafish at ‘Institute of Genomics and Integrative Biology (IGIB)’ under Dr. Sridhar Sivasubbu. Gold nanoparticles have already been implicated to cause severe deformities in blood vessel formation in mice. Here, I synthesized gold nanoparticles and studied their effect on vasculature development in fligata, a transgenic zebrafish. I screened for the phenotypes using confocal microscopy. I am interested in the area of organ transplants i.e. prosthetics and the problem of lack of communication between living and artificial materials. One of the greatest challenges encountered in the field is the need to have a functional vascular network for complex tissues and organs. The lack of capillary network connected to the host tissue and the resulting poor, oxygen transport limit the thickness of the generated tissue constructs to ~0.1 mm, which is generally too thin for clinical application that regulate cell differentiation. In addition, research is required to scale them up to considerable numbers for cell seeding into scaffolds.

Publications (1)

  • FishMap Zv8 update - a genomic regulatory map of zebrafish.

    • Bhartiya D M
    N/AReaders
    N/ACitations

Professional experience

Ph.D Student

IIT - Italian Institute of Technology, RBCS - Robotics, Brain and Cognitive Sciences Department

January 2011 - Present

Research Student

Institute of Genomics and Integrative Biology

October 2008 - June 2010(2 years)

Education

Masters in Biotechnology

Jiwaji University

July 2006 - September 2008(2 years)