Post-translational protein modifXRAYBioNMRLipidsGlycobiologyMetabolomicsBiosynthesisBiocatalysis & BiotransformationsMicroreactorsRecombinant Protein ExpressionProtein Separation and DetectionProtein Structural & Functional Analysis
Roland Wohlgemuth studied chemistry and biology at the University of Basel in Switzerland and obtained his Ph.D. at the Biocenter of the same university in 1979 working with Prof. Seelig on fundamental aspects of the structure and function of biological cell membranes. From 1980 to 1983 he moved to the University of California in Berkeley and did postdoctoral work on artificial photosynthesis with Prof. Melvin Calvin at the Lawrence Berkeley Laboratory and at UC Berkeley with a Swiss National Science Foundation Award followed by a two-year employment by the US Department of Energy. In 1983 Roland Wohlgemuth moved back to Buchs in Switzerland, where he built up biochemistry/biotechnology in the chemical company Fluka, which in 1989 became part of the Sigma-Aldrich Corporation. His main interests are in industrial innovation at the biology-chemistry-engineering interface, biocatalysis, glycobiology, metabolomics, protein analysis, bioanalytical technologies in general and in particular the development of tools and reagents for structural and functional analysis of proteins and their post-translational modification. He has started a new global initiative to develop methodologies for the analysis and preparation of central and remote metabolites.
CHAPTER 3: Biocatalytic Synthesis of Small Molecules - Past, Present and Future