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Spyridon Gerontas

  • Post-Doctoral Associate
  • 4h-indexImpact measure calculated using publication and citation counts. Updated daily.
  • 49CitationsNumber of citations received by Spyridon's publications. Updated daily.

Other IDs

Research interests

Biochemical Engineering

About

I am a biochemical engineer with expertise in the mathematical modelling of bioprocess unit operations currently employed as a Post-Doctoral Research Associate at the Department of Biochemical Engineering, UCL. After completing my undergraduate studies in Chemical Engineering at the National Technical University of Athens, Greece, I conducted postgraduate studies at the Department of Biochemical Engineering at University College London, UK. My doctorate focused on the field of tissue engineering. I developed mathematical models to predict the mass transfer requirements of a prototype bioreactor for the formation of tissue-engineered arteries. Novel ultra scale-down experiments were conducted to determine the parameters needed for such models using small quantities of cells. Additionally, I enhanced my knowledge in computational fluid dynamics and mathematical programming as well as in laboratory techniques most notably human cell culture, 3D cell culture, flow cytometry and oxygen / pH optical sensing. The main area of my research as a Post-Doctoral Research Associate at the Department of Biochemical Engineering, UCL lies in the modelling of bioprocess unit operations. As a member of this team, I am involved in the integration of mathematical models and experimentation to predict industrial scale chromatography and to enhance the structural properties of chromatographic resins improving their efficiency. I also participate in a joint project between the Department of Biochemical Engineering and the Liver Group in Royal Free Hospital, London for the design of a liver bioreactor. Furthermore, I assist PhD and MSc students in developing computational bioprocess models essential for their studies. My goal as biochemical engineer is to apply theoretical, experimental and computational methods for the design, evaluation and optimisation of bioprocess unit operations in collaboration with chemists, life scientists, mechanical engineers and surgeons.

Co-authors (33)

Publications (5)

  • A novel filtration system for point of care washing of cellular therapy products

    • Tostoes R
    • Dodgson J
    • Weil B
    • et al.
    N/AReaders
    0Citations
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  • Effects of bed compression on protein separation on gel filtration chromatography at bench and pilot scale

    • Kong D
    • Gerontas S
    • Mccluckie R
    • et al.
    N/AReaders
    0Citations
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  • Optimization-based framework for resin selection strategies in biopharmaceutical purification process development

    • Liu S
    • Gerontas S
    • Gruber D
    • et al.
    N/AReaders
    0Citations
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  • Optimal Resin Selection for Integrated Chromatographic Separations in High-Throughput Screening

    • Liu S
    • Gerontas S
    • Gruber D
    • et al.
    N/AReaders
    1Citations
    Get full text
  • Tuning evolutionary multiobjective optimization for closed-loop estimation of chromatographic operating conditions

    • Allmendinger R
    • Gerontas S
    • Titchener-Hooker N
    • et al.
    N/AReaders
    1Citations

Education history

PhD

Department of Biochemical Engineering, University College London

October 2003 - December 2007(4 years)

MSc

National Technical University of Athens (NTUA)

October 1995 - November 2000(5 years)