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Stephen Henderson

  • Dr
  • Bioinformatics Researcher
  • UCL Cancer Institute
  • --

    Readers

    Number of times these publications have been added to libraries on Mendeley.
  • 24

    Publications

    Number of items in this person’s My Publications folder on Mendeley.

Research interests

Machine Learning Genomics Data Mining Semantic Web Microarrays Cancer R Python Data Visualisation

About

I am a bioinformatics researcher (systems biology if you like- I don't like this name) in the Viral Oncology group within the new(ish) UCL Cancer Institute. I am studying a lot of microarray, microRNA and sequencing data. I am mainly involved with Kaposi Sarcoma, Carcinoma of Unkown Primary (CUP), Head and Neck Tumour trial data-- and lots more.... I'm from Glasgow, Scotland- where I was an undergraduate, before moving to Cambridge to do a PhD with Simon Laughlin and Roger Hardie on the statistics, electrophysiology and genetics of the Drosphila (Fruit-Fly) eye. Then I moved to London and worked in Parliament as a researcher, at Nature editing the website, and a few other jobs for a year or so. I decided after that to change scientific direction and become a little less specialised so I took a Masters (MRes) course in Bioinformatics at Birkbeck College. This led to a position in the Viral Oncology group within the Wolfson Institute at UCL with Chris Boshoff. More recently our group has now moved to the newly opened UCL Cancer Institute and I have become a Cancer Research UK employed researcher. Outside of work- I'm generally interested in computers, data mining, machine learning, Classics, Greek mythology, politics, jazz, techno, football, running, very loud parties and drinking-- in reverse order that is...

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Publications

An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.

  • Nelson A
  • Pillay N
  • Henderson S
  • Presneau N
  • Tirabosco R
  • Halai D
  • Berisha F
  • Flicek P
  • Stemple D
  • Stern C
  • Wardle F
  • Flanagan A
The Journal of pathology (2012)
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KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition.

  • Cheng F P
Cell Host Microbe (2011)
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DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.

  • Flanagan J
  • Kugler S
  • Waddell N
  • Johnstone C
  • Marsh A
  • Henderson S
  • Simpson P
  • da Silva L
  • Khanna K
  • Lakhani S
  • Boshoff C
  • Chenevix-Trench G
Breast cancer research : BCR (2010)
  • --

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KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming.

  • Hansen A
  • Henderson S
  • Lagos D
  • Nikitenko L
  • Coulter E
  • Roberts S
  • Gratrix F
  • Plaisance K
  • Renne R
  • Bower M
  • Kellam P
  • Boshoff C
Genes & development (2010)
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Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.

  • Flutter B
  • Edwards N
  • Fallah-Arani F
  • Henderson S
  • Chai J
  • Sivakumaran S
  • Ghorashian S
  • Bennett C
  • Freeman G
  • Sykes M
  • Chakraverty R
The Journal of clinical investigation (2010)
  • --

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Professional experience

Bioinformatics Researcher

UCL Cancer Institute

October 2002 - Present

Education history

Birkbeck College, University of London

MRes Bioinformatics

October 2000 - June 2001 (8 months)

University of Cambridge

PhD (Zoology Dept, Anatomy Dept)

October 1994 - June 1998 (4 years)

University of Glasgow

BSc Cell Biology

October 1990 - June 1994 (4 years)