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Stephen Henderson

  • Dr
  • Bioinformatics Researcher
  • UCL Cancer Institute
  • --

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  • 24

    Publications

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Research interests

Data VisualisationPythonRCancerMicroarraysSemantic WebData MiningGenomicsMachine Learning

About

I am a bioinformatics researcher (systems biology if you like- I don't like this name) in the Viral Oncology group within the new(ish) UCL Cancer Institute. I am studying a lot of microarray, microRNA and sequencing data. I am mainly involved with Kaposi Sarcoma, Carcinoma of Unkown Primary (CUP), Head and Neck Tumour trial data-- and lots more.... I'm from Glasgow, Scotland- where I was an undergraduate, before moving to Cambridge to do a PhD with Simon Laughlin and Roger Hardie on the statistics, electrophysiology and genetics of the Drosphila (Fruit-Fly) eye. Then I moved to London and worked in Parliament as a researcher, at Nature editing the website, and a few other jobs for a year or so. I decided after that to change scientific direction and become a little less specialised so I took a Masters (MRes) course in Bioinformatics at Birkbeck College. This led to a position in the Viral Oncology group within the Wolfson Institute at UCL with Chris Boshoff. More recently our group has now moved to the newly opened UCL Cancer Institute and I have become a Cancer Research UK employed researcher. Outside of work- I'm generally interested in computers, data mining, machine learning, Classics, Greek mythology, politics, jazz, techno, football, running, very loud parties and drinking-- in reverse order that is...

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Following (12)

  • Neha Ghevaria

    Neha Ghevaria

  • Christopher Yau

    Christopher YauUniversity of Birmingham, Birmingham

  • Richard Baird

    Richard BairdUniversity of Cambridge

  • Daniel Brewer

    Daniel BrewerUniversity of East Anglia Norwich Medical School

  • Mingyu Liu

    Mingyu LiuBarclays Capital

  • bendelin hernandez

    bendelin hernandez

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Publications

An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.

  • Nelson A
  • Pillay N
  • Henderson S
The Journal of pathology (2012)
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KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition.

  • Cheng F P
Cell Host Microbe (2011)
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DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.

  • Flanagan J
  • Kugler S
  • Waddell N
Breast cancer research : BCR (2010)
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KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming.

  • Hansen A
  • Henderson S
  • Lagos D
Genes & development (2010)
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Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.

  • Flutter B
  • Edwards N
  • Fallah-Arani F
The Journal of clinical investigation (2010)
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Professional experience

Bioinformatics Researcher

UCL Cancer Institute

October 2002 - Present

Education history

MRes Bioinformatics

Birkbeck College, University of London

October 2000 - June 2001(8 months)

PhD (Zoology Dept, Anatomy Dept)

University of Cambridge

October 1994 - June 1998(4 years)

BSc Cell Biology

University of Glasgow

October 1990 - June 1994(4 years)