Acute lymphoblastic leukemia with pancytopenia at presentation: Clinical correlates, prognostic impact, and association with survival

  • Kulkarni K
  • Marwaha R
  • 12


    Mendeley users who have this article in their library.
  • 2


    Citations of this article.


Acute lymphoblastic leukemia has a wide variety of presentations. There is paucity of any data addressing pancytopenia at presentation in acute lymphoblastic leukemia. In this study we assessed 84 patients with pancytopenia at presentation. They had a significantly lower incidence of bulky disease at presentation. A significantly higher fraction of these patients (n=66, 78.57%) opted for therapy (P=0.005) as compared with the rest. The estimated mean survival in patients presenting with pancytopenia (67.2+/-17.2 mo) was significantly higher (P=0.031, log-rank test) as compared with that of other patients (47.2+/-7.4 mo). Pancytopenia was an independent predictor of better survival (P=0.043) in multivariate analysis.

Author-supplied keywords

  • acute lymphoblastic leukemia
  • aplastic
  • outcome
  • pancytopenia
  • prognostic impact
  • resource limited

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Ketan P. Kulkarni

  • Ram K. Marwaha

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free