Adjuvant versus salvage radiation therapy for prostate cancer and the risk of death

  • D'Amico A
  • Chen M
  • Sun L
 et al. 
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Abstract

OBJECTIVE To investigate whether salvage radiation therapy (RT) for prostate-specific antigen (PSA) failure can provide the same result as adjuvant RT, which decreases the risk of all-cause mortality (ACM) for men with positive margins (R1), or extra-capsular or seminal vesicle extension (pT3). METHODS We studied 1638 men at Duke University who underwent radical prostatectomy for unfavourable-risk prostate cancer and whose postoperative PSA was undetectable. Cox regression was used to evaluate whether salvage vs adjuvant RT in men with a rapid (

Author-supplied keywords

  • mortality
  • prostate cancer
  • radiation therapy
  • radical prostatectomy

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Authors

  • A.V. D'Amico

  • M.-H. Chen

  • L. Sun

  • W.R. Lee

  • V. Mouraviev

  • C.N. Robertson

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