Aggressive early crystalloid resuscitation adversely affects outcomes in adult blunt trauma patients: An analysis of the Glue Grant database

  • Kasotakis G
  • Sideris A
  • Yang Y
 et al. 
  • 72

    Readers

    Mendeley users who have this article in their library.
  • 56

    Citations

    Citations of this article.

Abstract

Background—Evidence suggests that aggressive crystalloid resuscitation is associated with significant morbidity in various clinical settings. We wanted to assess whether aggressive early crystalloid resuscitation adversely affects outcomes in adult blunt trauma patients. Methods—Data were derived from the Glue Grant database. Our primary outcome measure was all-cause in-hospital mortality. Secondary outcomes included days on mechanical ventilation; intensive care unit (ICU) and hospital length of stay (LOS); inflammatory - (acute lung injury and respiratory distress syndrome [ALI/ARDS], multiple organ failure [MOF]) and resuscitationrelated morbidity (abdominal and extremity compartment syndromes, acute renal failure) and nosocomial infections (ventilator associated pneumonia [VAP], bloodstream [BSI], urinary tract [UTI] and surgical site infections [SSI]). Results—In our sample of 1,754 patients, in-hospital mortality was not affected, but ventilator days (p

Author-supplied keywords

  • Crystalloid
  • Glue Grant
  • blunt trauma
  • outcomes
  • resuscitation

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Authors

  • George Kasotakis

  • Antonis Sideris

  • Yuchiao Yang

  • Marc De Moya

  • David R. King

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free