Alcohol and cannabis use and mortality in people with schizophrenia and related psychotic disorders

  • Koola M
  • McMahon R
  • Wehring H
 et al. 
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Abstract

The impact of co-morbid substance use on mortality is not well studied in psychotic disorders. The objective of this study was to examine the impact of substance use on mortality in people with psychotic disorders and alcohol and/or drug use. We examined the rate of substance use and the risk of substance use on mortality risk over a 4-10 year period in 762 people with psychotic disorders. Deceased patients were identified from the Social Security Death Index and the Maryland Division of Vital Records. Substance use was defined as regular and heavy use or abuse or dependence. Seventy seven percent had co-morbid lifetime substance use, with co-morbid cannabis and alcohol use occurring most commonly. Out of 762 subjects, 62 died during follow up. In a Cox model, predicted mortality risk was higher in age group 35-55 compared to

Author-supplied keywords

  • Adult
  • Alcoholism/*epidemiology
  • Comorbidity
  • Female
  • Humans
  • Male
  • Marijuana Abuse/*epidemiology
  • Maryland/epidemiology
  • Middle Aged
  • Psychotic Disorders/*epidemiology/*mortality
  • Retrospective Studies
  • Risk Factors
  • Schizophrenia/*epidemiology/*mortality
  • Survival Analysis

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Authors

  • M M Koola

  • R P McMahon

  • H J Wehring

  • F Liu

  • K M Mackowick

  • K R Warren

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