Alkylresorcinol derivatives and sesquiterpene lactones from Cichorium spinosum

  • Melliou E
  • Magiatis P
  • Skaltsounis A
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Abstract

One new alkylresorcinol derivative, cichoriol B, and a mixture of three other ones, cichoriols A, C, and D, were isolated from the dichloromethane extract of Cichorium spinosum, a plant that is used traditionally in the Cretan diet. The methanol extract afforded one new sesquiterpene lactone, (4R)-3,4-dihydrolactucopicrin. The structures of the new compounds were determined by spectroscopic methods, mainly by the concerted application of 1D and 2D NMR techniques (HMQC, HMBC, NOESY).

Author-supplied keywords

  • 3,4-dihydrolactucopicrin
  • Alkylresorcinols
  • Cichoriols A-D
  • Cichorium spinosum
  • Lactucopicrin
  • Terpenoids

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Authors

  • Eleni Melliou

  • Prokopios Magiatis

  • Alexios Leandros Skaltsounis

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