Amphibian ocular malformation associated with frog virus 3

  • Burton E
  • Miller D
  • Styer E
 et al. 
  • 27


    Mendeley users who have this article in their library.
  • 10


    Citations of this article.


During an on-going amphibian ecology study, a free-ranging American bullfrog (Rana catesbeiana) metamorph was captured in a pitfall trap adjacent to a constructed farm pond at the Plateau Research and Education Center (PREC) on the Cumberland Plateau near Crossville, Tennessee, USA. Grossly, the right eye was approximately 50% the size of the left. Stereo and light microscopic examination revealed two granulomas within the orbit. Electron microscopic examination revealed virus particles scattered throughout one structure but mostly aggregated toward the center. Subsequent PCR and sequencing (GenBank accession Number EF175670) confirmed frog virus 3 (FV3). This represents the first report of a malformation in an anuran associated with FV3. © 2007 Elsevier Ltd. All rights reserved.

Author-supplied keywords

  • Amphibian
  • FV3
  • Metamorph
  • Ocular malformation
  • Rana catesbeiana

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • Elizabeth C. Burton

  • Debra L. Miller

  • Eloise L. Styer

  • Matthew J. Gray

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free