Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma

  • Zhang K
  • Chu K
  • Wu X
 et al. 
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Abstract Fibroblast growth factor (FGF) receptor (FGFR) substrate 2 ( FRS2 ) is an adaptor protein that plays a critical role in FGFR signaling . FRS2 is located on chromosome 12q13- 15 that is frequently amplified in liposarcomas. The significance of FRS2 and FGFR ...

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  • Keqiang Zhang

  • Kevin Chu

  • Xiwei Wu

  • Hanlin Gao

  • Jinhui Wang

  • Yate Ching Yuan

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