Anatomy and physiology of the human eye: Effects of mucopolysaccharidoses disease on structure and function - a review

  • Willoughby C
  • Ponzin D
  • Ferrari S
 et al. 
  • 2


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


Abstract: The current paper provides an overview of current knowledge on the structure and function of the eye. It describes in depth the different parts of the eye that are involved in the ocular manifestations seen in the mucopolysaccharidoses (MPS). The MPS are a group of rare inheritable lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs) in cells and tissues all over the body, leading to widespread tissue and organ dysfunction. GAGs also tend to accumulate in several tissues of the eye, leading to various ocular manifestations affecting both the anterior (cornea, conjunctiva) and the posterior parts (retina, sclera, optic nerve) of the eye. 2010 The Authors. Journal compilation 2010 Royal Australian and New Zealand College of Ophthalmologists.

Author-supplied keywords

  • Anatomy Eye disease Mucopolysaccharidosis Physiolo

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in


  • C E Willoughby

  • D Ponzin

  • S Ferrari

  • A Lobo

  • K Landau

  • Y Omidi

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free