Antenatal mindfulness intervention to reduce depression, anxiety and stress: a pilot randomised controlled trial of the MindBabyBody program in an Australian tertiary maternity hospital

  • H W
  • K M
  • F J
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Background: Mindfulness interventions to reduce psychological distress are well-suited to pregnancy, due to theirbrief and non-pharmacological nature, but there is a need for more robust evidence determining their usefulness.This pilot study was designed to explore the feasibility of a randomised controlled trial of a mindfulness intervention toreduce antenatal depression, anxiety and stress.Methods: The study was designed in two parts 1) a non-randomised trial targeting women at risk of mental healthproblems (a selected population) and 2) a randomised controlled trial (RCT) of a universal population. Process evaluationfocused on feasibility of recruitment pathways, participant retention, acceptability of study measures, and engagementwith mindfulness practices. Measurement of psychological distress was taken pre and post intervention through theCentre for Epidemiologic Studies Depression Scale Revised, the Depression Anxiety and Stress Scale-21, the State-TraitAnxiety Inventory, and the Perceived Stress Scale.Results: 20 women were recruited to the non-randomised trial, and 32 to the RCT. Recruitment through a mailed studybrochure at the time of booking-in to the hospital resulted in the largest number of participants in the RCT (16/32;50%), and resulted in considerably earlier recruitment (50% in first trimester, 50% second trimester) compared torecruitment through the antenatal clinic waiting room (86% in second trimester, 14% third trimester). Over athird of women in the universal population scored above clinical cut-offs for depression and anxiety, indicating asample with more symptomology than the general population. The most common reason for loss to follow-up wasdelivery of baby prior to follow-up (n = 9). In the non-randomised study, significant within group improvements todepression and anxiety were observed. In the intervention arm of the RCT there were significant within groupimprovements to anxiety and mindfulness. No between group differences for the intervention and 'care asusual' control group were observed.Conclusions: This small pilot study provides evidence on the feasibility of an antenatal mindfulness intervention toreduce psychological distress. Major challenges include: finding ways to facilitate recruitment in early pregnancy andengaging younger women and other vulnerable populations.Trial registration: Australian New Zealand Clinical Trials Registry ACTRN12613000742774 (31/10/2012).

Author-supplied keywords

  • 12613000742774
  • Australia
  • Depression Anxiety and Stress Scale 21
  • MindBabyBody program
  • Perceived Stress Scale
  • State Trait Anxiety Inventory
  • adult
  • anxiety
  • article
  • controlled study
  • distress syndrome
  • feasibility study
  • female
  • health program
  • human
  • major clinical study
  • maternal stress
  • mental health
  • mindfulness
  • pilot study
  • prenatal period
  • puerperal depression
  • quality of life
  • randomized controlled trial
  • rating scale
  • self report
  • tertiary care center

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  • Woolhouse H

  • Mercuri K

  • Judd F

  • Brown SJ

  • H Woolhouse

  • K Mercuri

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