Antenatal thyroid correlates of postpartum depression

  • Pedersen C
  • Johnson J
  • Silva S
 et al. 
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We previously found significantly higher T3-resin uptake and nearly significantly lower total thyroxine concentrations at 38 weeks of pregnancy in women with higher postpartum depression ratings. This study further examined the relationship between thyroid status during late pregnancy and antenatal and postpartum depression scores. Thyroid measures were obtained at 32-35, 36, and 37 weeks of pregnancy in 31 women with normal range thyroid hormone levels. Subjects rated their mood at these antenatal time points and every other week between postpartum weeks 2 and 24 on the Edinburgh Postnatal Depression Scale and the Beck Depression Inventory. Mean antenatal thyroxine concentrations and free thyroxine indices correlated significantly and negatively with mean depression scores during each of three postpartum time periods (postpartum weeks 2-6, 14-18, 20-24). Women with total and free thyroxine concentrations that were, respectively,

Author-supplied keywords

  • Antenatal
  • Beck Depression Inventory
  • Depression
  • Edinburgh Postnatal Depression Scale
  • Postpartum
  • Thyroid

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  • Cort A. Pedersen

  • Jacqueline L. Johnson

  • Susan Silva

  • Robertas Bunevicius

  • Samantha Meltzer-Brody

  • Robert M. Hamer

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