Antidepressants in chronic neuropathic pain.

  • Mattia C
  • Coluzzi F
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This review presents available clinical studies and new insights into mechanisms of analgesic effect and possible new routes of administration of antidepressant drugs. Older TCAs continue to be superior treatments. We focused on recent findings on newer antidepressants as analgesics. Their use should be supported by further controlled trials.

Author-supplied keywords

  • Analgesics
  • Analgesics: pharmacology
  • Animals
  • Antidepressive Agents
  • Antidepressive Agents, Second-Generation
  • Antidepressive Agents, Second-Generation: pharmaco
  • Antidepressive Agents, Second-Generation: therapeu
  • Antidepressive Agents, Tricyclic
  • Antidepressive Agents, Tricyclic: pharmacology
  • Antidepressive Agents, Tricyclic: therapeutic use
  • Antidepressive Agents: pharmacology
  • Antidepressive Agents: therapeutic use
  • Humans
  • Monoamine Oxidase Inhibitors
  • Monoamine Oxidase Inhibitors: pharmacology
  • Monoamine Oxidase Inhibitors: therapeutic use
  • Pain
  • Pain: drug therapy
  • Peripheral Nervous System Diseases
  • Peripheral Nervous System Diseases: drug therapy
  • Serotonin Uptake Inhibitors
  • Serotonin Uptake Inhibitors: pharmacology
  • Serotonin Uptake Inhibitors: therapeutic use

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  • Consalvo Mattia

  • Flaminia Coluzzi

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