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Journal article

Antifungal activity of fluid extract and essential oil from anise fruits (Pimpinella anisum L., Apiaceae).

Kosalec I, Pepeljnjak S, Kustrak D ...see all

Acta pharmaceutica, vol. 55, issue 4 (2005) pp. 377-385

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Abstract

Antifungal activities of fluid extract and essential oil obtained from anise fruits Pimpinella anisum L. (Apiaceae) were tested in vitro on clinical isolates of seven species of yeasts and four species of dermatophytes. Diffusion method with cylinders and the broth dilution method were used for antifungal activity testing. Anise fluid extract showed antimycotic activity against Candida albicans, C. parapsilosis, C. tropicalis, C. pseudotropicalis and C. krusei with MIC values between 17 and 20% (v/v). No activity was noticed against C. glabrata, and anis fruits extracts showed growth promotion activity on Geotrichum spp. Anise fruits extract inhibited the growth of dermatophyte species (Trichophyton rubrum, T. mentagrophytes, Microsporum canis and M. gypseum) with MIC values between 1.5 and 9.0% (V/V). Anise essential oil showed strong antifungal activity against yeasts with MIC lower than 1.56% (V/V) and dermatophytes with MIC lower than 0.78% (V/V). Significant differences in antifungal activities were found between anise fluid extract and anise essential oil (p

Author-supplied keywords

  • anise
  • anise fruit
  • antifungal activity
  • apiaceae
  • candida
  • essential oil
  • fluid extract
  • pimpinella anisum

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Authors

  • Ivan Kosalec

  • Stjepan Pepeljnjak

  • Danica Kustrak

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