Antimicrobial prophylaxis in surgical interventions

  • Van Der Werken C
  • Van Putten P
  • Van Vroonhoven T
  • 1

    Readers

    Mendeley users who have this article in their library.
  • N/A

    Citations

    Citations of this article.

Abstract

The use of antibiotic prophylaxis was prospectively evaluated in 1,021 surgical patients from 27 hospitals in metropolitan Minnesota. The majority of patients had undergone general surgical (23%), obstetric and gynecologic (13%), orthopedic (26%), and urologic (12%) procedures. One half of the courses of antibiotic prophylaxis were given to patients undergoing clean (class 1) surgery. Antibiotics were first administered in the four hours preceding the start of surgery in only 41% of the patients. The mean duration of prophylaxis was 3.4 days. About one third of the patients received prophylaxis for more than 72 hours; this group accounted for 65% of patient-days of antibiotic administration. More than one half of the patients received a cephalosporin. Analysis of patient charges suggests that 18% to 50% of the cost of perioperative antibiotic prophylaxis might be saved by limiting the duration of drug administration.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

There are no full text links

Authors

  • C Van Der Werken

  • P L Van Putten

  • T J Van Vroonhoven

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free