Apparent diffusion coefficient and diffusion-weighted signal intensity of the interpeduncle region of the midbrain in adults: Initial evaluation

Abstract

Objective: The diffusion-weighted signal intensity (SI) of the interpeduncle region (IPR) of the midbrain has not been fully understood. This study was to evaluate the apparent diffusion coefficient (ADC) and SI of the IPR on axial diffusion-weighted imaging (DWI). Methods: Axial brain DWI (4-mm slice thickness, no gap) was performed in 145 healthy subjects at 1.5T MR scanner. Correlations between the contrast-to-noise ratio (CNR) and ADC value in the IPR and age, gender were statistically analyzed. Results: The CNR was significantly higher in the IPR than in the periaqueductal gray (PAG) (P