Application of acute phase protein measurements in veterinary clinical chemistry

  • Petersen H
  • Nielsen J
  • Heegaard P
  • 30

    Readers

    Mendeley users who have this article in their library.
  • 502

    Citations

    Citations of this article.

Abstract

The body's early defence in response to trauma, inflammation or infection, the acute phase response, is a complex set of systemic reactions seen shortly after exposure to a triggering event. One of the many components is an acute phase protein response in which increased hepatic synthesis leads to increased serum concentration of positive acute phase proteins. The serum concentration of these acute phase proteins returns to base levels when the triggering factor is no longer present. This paper provides a review of the acute phase proteins haptoglobin, C-reactive protein and serum amyloid A and their possible use as non-specific indicators of health in large animal veterinary medicine such as in the health status surveillance of pigs at the herd level, for the detection of mastitis in dairy cattle and for the prognosis of respiratory diseases in horses.

Author-supplied keywords

  • Acute phase protein
  • C-reactive protein
  • Haptoglobin
  • Health surveillance
  • Mastitis
  • Respiratory disease
  • Serum amyloid A

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • Henrik Hagbard Petersen

  • Jens Peter Nielsen

  • Peter Mikael Helweg Heegaard

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free