Application of ATC/DDD methodology to evaluate of antibiotic use in a general hospital in Turkey.

  • Sözen H
  • Gönen I
  • Sözen A
 et al. 
  • 35


    Mendeley users who have this article in their library.
  • N/A


    Citations of this article.


BACKGROUND: The aim of this study is to evaluate in-house antibiotic use in a state hospital in Turkey with its cost, using the ATC/DDD index, which is an accepted standard method.

METHODS: This study was performed as a point prevalence study in a state hospital with 372 beds. All in-house patients using antibiotics on July 19, 2011 were included in the study. Indications for antibiotic use and information about the patients were recorded on special forms. Antibiotic use and cost analysis were evaluated using the ATC/DDD index, which is also suggested by the WHO to be used in similar studies.

FINDINGS: 147 patients out of 308 patients who were in-house were identified to use antibiotics with appropriate indications for prophylaxis or treatment in 61% of the patients. The rate of appropriate antibiotic use was identified to be in 78%, while this rate was 38.9% in surgical clinics. The daily cost of the antibiotics consumed on the date of the study was calculated as 4104.79 TL (=2476.80 USD).

DISCUSSION: The rate of inappropriate use of antibiotics seems to be high in our hospital. This will result in both increased costs and also increased nosocomial infection rates with resistant species. Infectious disease specialists should take more active roles in the in-house antibiotic use, hospitals should prepare and implement their own principles of antibiotic use, and microbiology laboratories should be used more effectively. These measures would decrease the conspicuous shortcomings in the antibiotic use.

Author-supplied keywords

  • Anti-Bacterial Agents
  • Anti-Bacterial Agents: economics
  • Anti-Bacterial Agents: therapeutic use
  • Bacterial Infections
  • Bacterial Infections: drug therapy
  • Drug Utilization Review
  • Drug Utilization Review: methods
  • Female
  • Hospitals, General
  • Humans
  • Inappropriate Prescribing
  • Inappropriate Prescribing: adverse effects
  • Inappropriate Prescribing: economics
  • Male
  • Physician's Practice Patterns
  • Prescription Drug Misuse
  • Prescription Drug Misuse: adverse effects
  • Prescription Drug Misuse: economics
  • Turkey
  • World Health Organization

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text


  • Hamdi Sözen

  • Ibak Gönen

  • Ayse Sözen

  • Ali Kutlucan

  • Serdar Kalemci

  • Murat Sahan

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free