Application of cancer procoagulant as an early detection tumor marker.

  • Kozwich D
  • Kramer L
  • Mielicki W
 et al. 
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Abstract

In spite of many advances in the analytical reagents (antibodies), analytical systems, and the clinical application of tumor markers, the present markers do not detect early stage cancer. Preliminary data with an antigen specific to tumor tissue, cancer procoagulant (CP), suggest its possible role in the detection of early stage cancer. This study was aimed at determining the clinical use of CP as an early stage tumor marker.

Author-supplied keywords

  • Adenocarcinoma
  • Adenocarcinoma: blood
  • Antigens, Tumor-Associated, Carbohydrate
  • Antigens, Tumor-Associated, Carbohydrate: blood
  • Blood Coagulation Factors
  • Blood Coagulation Factors: analysis
  • Breast Neoplasms
  • Breast Neoplasms: blood
  • Carcinoembryonic Antigen
  • Carcinoembryonic Antigen: blood
  • Carcinoma, Squamous Cell
  • Carcinoma, Squamous Cell: blood
  • Colonic Neoplasms
  • Colonic Neoplasms: blood
  • Cysteine Endopeptidases
  • Cysteine Endopeptidases: blood
  • Double-Blind Method
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Gastrointestinal Neoplasms
  • Gastrointestinal Neoplasms: blood
  • Humans
  • Male
  • Neoplasm Proteins
  • Neoplasms
  • Neoplasms: blood
  • Ovarian Neoplasms
  • Ovarian Neoplasms: blood
  • Prostatic Neoplasms
  • Prostatic Neoplasms: blood
  • Rectal Neoplasms
  • Rectal Neoplasms: blood
  • Sensitivity and Specificity
  • Tumor Markers, Biological
  • Tumor Markers, Biological: blood

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Authors

  • D L Kozwich

  • L C Kramer

  • W P Mielicki

  • S S Fotopoulos

  • S G Gordon

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