NK cells express receptors for polymorphic MHC class I molecules that inhibit killing of potential target cells bearing appropriate class I allotypes. Here we review the membrane receptors on human NK cells that are known to initiate cell-mediated cytotoxicity and demonstrate regulation of these responses by the killer cell inhibitory (KIR) receptors.
CITATION STYLE
Lanier, L. L., Corliss, B., & Phillips, J. H. (1997). Arousal and inhibition of human NK cells. Immunological Reviews. https://doi.org/10.1111/j.1600-065X.1997.tb00947.x
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