The development of synthetic agents able to hydrolytically cleave DNA with high efficiency and selectivity is a fascinating challenge that will show the way to obtaining artificial nucleases able to compete with the natural enzymes. This Feature Article highlights the progress reported toward the realization of synthetic nucleases with particular attention to the strategies that can be pursued to improve efficiency and sequence selectivity. © The Royal Society of Chemistry 2005.
CITATION STYLE
Mancin, F., Scrimin, P., Tecilla, P., & Tonellato, U. (2005, May 28). Artificial metallonucleases. Chemical Communications. Royal Society of Chemistry. https://doi.org/10.1039/b418164f
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