Association of the -2849 interleukin-10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis

  • Lard L
  • Van Gaalen F
  • Schonkeren J
 et al. 
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Abstract

To analyze the -2849 A/G interleukin-10 (IL-10) promoter polymorphism, which is associated with high (AG/GG) and low (AA) IL-10 production, in a cohort of rheumatoid arthritis (RA) patients and controls in order to gain a better understanding of its role in the incidence and progression of RA.

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Authors

  • L. R. Lard

  • F. A. Van Gaalen

  • J. J.M. Schonkeren

  • E. J. Pieterman

  • G. Stoeken

  • K. Vos

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