Association of anti-Chlamydia antibodies with ectopic pregnancy in Benin city, Nigeria: A case-control study

  • Agholor K
  • Omo-Aghoja L
  • Okonofua F
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BACKGROUND Ectopic pregnancy remains a major public health problem especially in many developing countries where it is a significant contributor to pregnancy related morbidity and mortality. OBJECTIVE To determine the association between prior Chlamydia trachomatis infection and the risk of ectopic pregnancy. METHODS A case-control study from two tertiary health care facilities in Benin City, Nigeria. Ninety eight women with ectopic pregnancy (cases) and another 98 women with uncomplicated intrauterine pregnancy (controls) matched for age, were interviewed using a semi-structured questionnaire and evaluated for serological evidence of prior Chlamydia trachomatis infection. RESULTS The antibody titres in cases (48%) were significantly higher than in controls (16.3%) (p

Author-supplied keywords

  • Anti-chlamydia antibodies
  • Ectopic pregnancy
  • Level of education
  • Sexual history
  • Vaginal discharge

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  • K. Agholor

  • Lawrence Omo-Aghoja

  • F. Okonofua

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