Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts

  • Connon S
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Cinchona alkaloid derivatives modified to include a (thio)urea component have emerged in the last three years as readily accessible, robust and tunable bifunctional organocatalysts for a range of synthetically useful transformations. The origins of these catalysts and the major developments in their application in enantioselective synthesis are reviewed.

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  • Stephen J. Connon

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