Ataxia with vitamin E deficiency: Biochemical effects of malcompliance with vitamin E therapy

  • Schuelke M
  • Finckh B
  • Sistermans E
 et al. 
  • 7


    Mendeley users who have this article in their library.
  • 8


    Citations of this article.


To prevent neuronal damage, patients with ataxia with isolated vitamin E deficiency need lifelong supplementation with high doses of vitamin E. Short interruptions of therapy, such as occur in malcompliance, do not lead to clinical symptoms. However, the authors show that even short withdrawals may cause a prolonged decrease of the total radical trapping capacity of plasma; its major contributors, such as urate and sulfhydryl groups, fail to compensate for the missing vitamin E.

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document


  • M. Schuelke

  • B. Finckh

  • E. A. Sistermans

  • M. G.E.M. Ausems

  • C. Hübner

  • A. Von Moers

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free