Bacterial adhesion and entry into host cells.

  • Pizarro-Cerdá J
  • Cossart P
  • Agerer F
 et al. 
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Abstract

Successful establishment of infection by bacterial pathogens requires adhesion to host cells, colonization of tissues, and in certain cases, cellular invasion-followed by intracellular multiplication, dissemination to other tissues, or persistence. Bacteria use monomeric adhesins/invasins or highly sophisticated macromolecular machines such as type III secretion systems and retractile type IV pili to establish a complex host/pathogen molecular crosstalk that leads to subversion of cellular functions and establishment of disease.

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Authors

  • Javier Pizarro-Cerdá

  • Pascale Cossart

  • F. Agerer

  • S. Lux

  • A. Michel

  • M. Rohde

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