Bacterial meningitis: An update of new treatment options

  • R. N
  • M. D
  • A. S
 et al. 
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Abstract

The outcome of bacterial meningitis critically depends on the rapid initiation of bactericidal antibiotic therapy and adequate management of septic shock. In community-acquired meningitis, the choice of an optimum initial empirical antibiotic regimen depends on the regional resistance patterns. Pathogens resistant to antibacterials prevail in nosocomial bacterial meningitis. Dexamethasone is recommended as adjunctive therapy for community-acquired meningitis in developed countries. In comatose patients, aggressive measures to lower intracranial pressure

Author-supplied keywords

  • Escherichia coli
  • Glasgow outcome scale
  • Pneumococcus vaccine
  • Streptococcus pneumoniae
  • add on therapy
  • ampicillin
  • anastomosis
  • antibiotic therapy
  • aphasia
  • area under the curve
  • aseptic meningitis
  • bacterial meningitis
  • beta lactam antibiotic
  • blood brain barrier
  • brain perfusion
  • carbapenem derivative
  • cefepime
  • cefotaxime
  • ceftaroline
  • ceftazidime
  • ceftobiprole
  • ceftriaxone
  • central nervous system infection
  • cephalosporin
  • cerebrospinal fluid analysis
  • cerebrospinal fluid shunting
  • chloramphenicol
  • clinical feature
  • comatose patient
  • community acquired infection
  • computer assisted tomography
  • confusion
  • consciousness disorder
  • continuous infusion
  • corticosteroid
  • daptomycin
  • decompression surgery
  • decompressive craniectomy
  • dexamethasone
  • drug megadose
  • drug penetration
  • encephalitis
  • eosinophilic meningitis
  • facial nerve paralysis
  • fever
  • gaze paralysis
  • gentamicin
  • glycylcycline derivative
  • headache
  • hearing impairment
  • human
  • hydrocephalus
  • immunocompromised patient
  • immunomodulation
  • intracranial hypertension
  • intracranial pressure
  • linezolid
  • liver toxicity
  • lumbar puncture
  • mental disease
  • meropenem
  • methylprednisolone
  • metronidazole
  • minimum inhibitory concentration
  • mortality
  • moxifloxacin
  • nonhuman
  • pathophysiology
  • penicillin G
  • placebo
  • pleocytosis
  • quinoline derived antiinfective agent
  • review
  • sedation
  • seizure
  • septic shock
  • single drug dose
  • stiff neck
  • telavancin
  • therapeutic hyperventilation
  • tigecycline
  • trovafloxacin
  • unindexed drug
  • vancomycin
  • visual field defect
  • volume of distribution

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Authors

  • Nau R.

  • Djukic M.

  • Spreer A.

  • Ribes S.

  • Eiffert H.

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