Beta-2 receptor antagonists for acute traumatic brain injury.

  • Ker K
  • Blackhall K
  • 3

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Abstract

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Cerebral oedema, the accumulation of fluid within the brain, is believed to be an important contributor to the secondary brain damage that occurs following injury. The release of kinins is thought to be an important factor in the development of cerebral vasogenic oedema and the use of beta-2 receptor antagonists, which prevent the release of these kinins, have been proposed as a potential therapeutic intervention.

Author-supplied keywords

  • Acute Disease
  • Adrenergic beta-2 Receptor Antagonists
  • Brain Edema
  • Brain Edema: drug therapy
  • Brain Injuries
  • Brain Injuries: drug therapy
  • Brain Injuries: mortality
  • Humans
  • Intracranial Pressure
  • Peptides
  • Peptides: therapeutic use
  • Quinolines
  • Quinolines: therapeutic use
  • Randomized Controlled Trials as Topic

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Authors

  • K Ker

  • K Blackhall

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