Crayfish were exposed to intermediate concentrations of lead nitrate (150 μgl-1) and 1100 μgl-1) for periods up to 7 weeks. Lead clearance was monitored at 3 weeks following the 7 week exposure to the lower concentration. Lead bioaccumulation was demonstrated to be a time- and dose-dependent phenomenon in gills, hepatopancreas and abdominal muscle, but not the exoskeleton. The tissue concentrations of lead in soft tissues, in decreasing order were gills > hepatopancreas > muscle > hemolymph. Lead clearance was significant in all tissues evaluated except the hepatopancreas, the organ of metal storage and detoxification.
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