Blood volume measurement to guide fluid therapy after aneurysmal subarachnoid hemorrhage: a prospective controlled study.

  • Hoff R
  • Rinkel G
  • Verweij B
 et al. 
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Background and Purpose: Conventional parameters used to guide fluid therapy after aneurysmal subarachnoid hemorrhage (SAH) are poorly related to blood volume. In a prospective controlled study we assessed whether fluid management guided by daily measurements of blood volume (BV) reduces the incidence of severe hypovolemia compared to conventional fluid balance guided fluid therapy.Methods: We used Pulse Dye Densitometry to measure BV daily in 102 patients during the first 10 days after SAH. Fluid management was based on BV-measurements in the intervention group (n=54) and on fluid balance in the control group (n=48). Severe hypovolemia was defined as BV

Author-supplied keywords

  • Adult
  • Aged
  • Blood Volume
  • Blood Volume Determination -- Methods
  • Clinical Trials
  • Densitometry
  • Female
  • Fluid Therapy -- Methods
  • Human
  • Male
  • Middle Age
  • Outcome Assessment
  • Prospective Studies
  • Subarachnoid Hemorrhage -- Complications
  • Subarachnoid Hemorrhage -- Therapy

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  • R Hoff

  • G Rinkel

  • B Verweij

  • A Algra

  • C Kalkman

  • Reinier Hoff

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