Bogorol A Produced in Culture by a Marine Bacillus sp. Reveals a Novel Template for Cationic Peptide Antibiotics

  • Barsby T
  • Kelly M
  • Gagné S
 et al. 
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[figure: see text] Bogorol A (1), a novel peptide antibiotic active against MRSA and VRE, has been isolated from cultures of a marine Bacillus sp. collected in Papua New Guinea. The structure of bogorol A was elucidated by a combination of spectroscopic analyses and chemical degradation. Bogorol A illustrates a new structural template for "cationic peptide antibiotics".

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  • Todd Barsby

  • Michael T. Kelly

  • Stéphane M. Gagné

  • Raymond J. Andersen

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