A broad survey of recombination in animal mitochondria

  • Piganeau G
  • Gardner M
  • Eyre-Walker A
  • 138

    Readers

    Mendeley users who have this article in their library.
  • 112

    Citations

    Citations of this article.

Abstract

Recombination in mitochondrial DNA (mtDNA) remains a controversial topic. Here we present a survey of 279 animal mtDNA data sets, of which 12 were from asexual species. Using four separate tests, we show that there is widespread evidence of recombination; for one test as many as 14.2% of the data sets reject a model of clonal inheritance and in several data sets, including primates, the recombinants can be identified visually. We show that none of the tests give significant results for obligate clonal species (apomictic pathogens) and that the sexual species show significantly greater evidence of recombination than asexual species. For some data sets, such as Macaca nemestrina, additional data sets suggest that the recombinants are not artifacts. For others, it cannot be determined whether the recombinants are real or produced by laboratory error. Either way, the results have important implications for how mtDNA is sequenced and used.

Author-supplied keywords

  • Clonal inheritance
  • Macaca nemestrina
  • Recombination
  • mtDNA

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

Get full text

Authors

  • Gwenaël Piganeau

  • Michael Gardner

  • Adam Eyre-Walker

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free