A broadly applicable copper reagent for trifluoromethylations and perfluoroalkylations of aryl iodides and bromides

  • Morimoto H
  • Tsubogo T
  • Litvinas N
 et al. 
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A copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with Togni's reagent was described. The reaction proceeded in good to excellent yields for a range of different substrates including heteroarylboronic acids and substrates with a variety of functional groups under mild reaction conditions.

Author-supplied keywords

  • Aryl halide
  • Copper
  • Cross coupling
  • Trifluoromethylation

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