The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activation

  • Mamane Y
  • Chan C
  • Lavallee G
 et al. 
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Abstract

... C3aR −/− mice had improved insulin sensitivity on both ND and HFD as seen ... Increasing literature suggests that metabolic disorders such as diabetes, obesity, and atherosclerosis also ... infer causal relationships between gene expression and complex genetic diseases such as ...

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Authors

  • Chi Chung Chan

  • Genevieve Lavallee

  • Nicolas Morin

  • Li Jing Xu

  • Jing Qi Huang

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