Cancer invasion and metastasis

  • Kim Y
  • Liotta L
  • Kohn E
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Abstract

Mechanisms by which primary tumors invade local tissues and spread to distant sites are beginning to be understood. Included are factors involved in cell-to-cell and cell-to-extracellular matrix interactions, motility factors, and genetic controls. Knowledge of such mechanisms is spurring development of novel therapeutic agents for clinical study.

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Authors

  • Y.S. Kim

  • L.A. Liotta

  • E.C. Kohn

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