Cardiovascular risk factors in adolescents

  • 1

    Readers

    Mendeley users who have this article in their library.
  • N/A

    Citations

    Citations of this article.

Abstract

Most children who are normal weight for height and otherwise healthy have risk factor levels associated with the absence of heart disease (ie, they do not smoke, do not have diabetes, are physically active, have low-density lipoprotein levels < 110 mg/dL, and have blood pressure < 120/80 mm Hg). However, by adolescence, the earliest lesions in the atherosclerotic process, fatty streaks and raised lesions, are present in the coronary arteries and the abdominal aorta. The severity of early atherogenesis is related to the coexistence of the major cardiovascular risk factors. Most commonly, the associated risk disturbances are mild: borderline hypertension, mild dyslipidemia, insulin resistance, overweight, physical inactivity, and initiation of tobacco use. Rarely, more severe risk factors are present: familial hypercholesterolemia (a genetic disorder of lipid metabolism), diabetes mellitus, secondary hypertension of long standing, or risk factors associated with chronic conditions such as end-stage renal disease. Thus, cardiovascular risk management in this age group has two components: primordial prevention (the prevention of the development of cardiovascular risk in the first place) and primary prevention (more aggressive treatment of identified risk factors in high-risk individuals either through behavioral or pharmacologic means). Trials beginning in adolescence of the primary prevention of atherosclerosis-related diseases have not been undertaken; thus, the decision to initiate pharmacologic management in high-risk adolescents requires careful thought. Copyright © 2006 by Current Science Inc.

Author-supplied keywords

  • *adolescent disease/co [Complication]
  • *adolescent disease/di [Diagnosis]
  • *adolescent disease/dt [Drug Therapy]
  • *adolescent disease/et [Etiology]
  • *adolescent disease/pc [Prevention]
  • *adolescent disease/th [Therapy]
  • *cardiovascular disease/co [Complication]
  • *cardiovascular disease/di [Diagnosis]
  • *cardiovascular disease/dt [Drug Therapy]
  • *cardiovascular disease/et [Etiology]
  • *cardiovascular disease/pc [Prevention]
  • *cardiovascular disease/th [Therapy]
  • abdominal aorta
  • acetylsalicylic acid/cb [Drug Combination]
  • acetylsalicylic acid/dt [Drug Therapy]
  • adolescent
  • amlodipine/ae [Adverse Drug Reaction]
  • amlodipine/do [Drug Dose]
  • amlodipine/dt [Drug Therapy]
  • angioneurotic edema/si [Side Effect]
  • angiotensin receptor antagonist/ae [Adverse Drug R
  • angiotensin receptor antagonist/do [Drug Dose]
  • angiotensin receptor antagonist/dt [Drug Therapy]
  • atenolol/ae [Adverse Drug Reaction]
  • atenolol/do [Drug Dose]
  • atenolol/dt [Drug Therapy]
  • atherogenesis
  • atorvastatin/ae [Adverse Drug Reaction]
  • atorvastatin/do [Drug Dose]
  • atorvastatin/dt [Drug Therapy]
  • atorvastatin/it [Drug Interaction]
  • behavior modification
  • beta adrenergic receptor blocking agent/ae [Advers
  • beta adrenergic receptor blocking agent/do [Drug D
  • beta adrenergic receptor blocking agent/dt [Drug T
  • bloating/si [Side Effect]
  • body height
  • body weight
  • bradycardia/si [Side Effect]
  • calcium channel blocking agent/ae [Adverse Drug Re
  • calcium channel blocking agent/do [Drug Dose]
  • calcium channel blocking agent/dt [Drug Therapy]
  • cholesterol blood level
  • cigarette smoking
  • colestyramine/do [Drug Dose]
  • colestyramine/dt [Drug Therapy]
  • constipation/si [Side Effect]
  • coronary artery
  • coughing/si [Side Effect]
  • diabetes mellitus
  • diastolic blood pressure
  • diet therapy
  • dipeptidyl carboxypeptidase inhibitor/ae [Adverse
  • dipeptidyl carboxypeptidase inhibitor/do [Drug Dos
  • dipeptidyl carboxypeptidase inhibitor/dt [Drug The
  • disease severity
  • diuretic agent/ae [Adverse Drug Reaction]
  • diuretic agent/do [Drug Dose]
  • diuretic agent/dt [Drug Therapy]
  • drug contraindication
  • drug dose regimen
  • drug potentiation
  • dyslipidemia
  • electrocardiography
  • electrolyte disturbance/si [Side Effect]
  • exercise
  • ezetimibe/do [Drug Dose]
  • ezetimibe/dt [Drug Therapy]
  • ezetimibe/it [Drug Interaction]
  • familial hypercholesterolemia/dt [Drug Therapy]
  • fish oil/dt [Drug Therapy]
  • flatulence/si [Side Effect]
  • flushing
  • gastrointestinal symptom/si [Side Effect]
  • gynecomastia/si [Side Effect]
  • hepatitis/si [Side Effect]
  • high risk population
  • hospitalization
  • human
  • hydrochlorothiazide/do [Drug Dose]
  • hydrochlorothiazide/dt [Drug Therapy]
  • hyperkalemia/si [Side Effect]
  • hypertension/di [Diagnosis]
  • hypertension/dt [Drug Therapy]
  • hypertriglyceridemia/dt [Drug Therapy]
  • hyperuricemia/si [Side Effect]
  • immobilization
  • insulin resistance
  • kidney failure
  • lisinopril/ae [Adverse Drug Reaction]
  • lisinopril/do [Drug Dose]
  • lisinopril/dt [Drug Therapy]
  • liver dysfunction/si [Side Effect]
  • losartan/ae [Adverse Drug Reaction]
  • losartan/do [Drug Dose]
  • losartan/dt [Drug Therapy]
  • low density lipoprotein cholesterol/ec [Endogenous
  • malabsorption/si [Side Effect]
  • medical decision making
  • mevinolin/ae [Adverse Drug Reaction]
  • mevinolin/do [Drug Dose]
  • mevinolin/dt [Drug Therapy]
  • myalgia/si [Side Effect]
  • nicotinic acid/ae [Adverse Drug Reaction]
  • nicotinic acid/cb [Drug Combination]
  • nicotinic acid/do [Drug Dose]
  • nicotinic acid/dt [Drug Therapy]
  • obesity
  • omega 3 fatty acid/dt [Drug Therapy]
  • physical activity
  • pravastatin/ae [Adverse Drug Reaction]
  • pravastatin/do [Drug Dose]
  • pravastatin/dt [Drug Therapy]
  • pravastatin/it [Drug Interaction]
  • primary prevention
  • protein analysis
  • review
  • risk factor
  • risk management
  • simvastatin/ae [Adverse Drug Reaction]
  • simvastatin/do [Drug Dose]
  • simvastatin/dt [Drug Therapy]
  • simvastatin/it [Drug Interaction]
  • spironolactone/ae [Adverse Drug Reaction]
  • spironolactone/do [Drug Dose]
  • spironolactone/dt [Drug Therapy]
  • systolic blood pressure
  • treatment indication
  • triacylglycerol/ec [Endogenous Compound]

Get free article suggestions today

Mendeley saves you time finding and organizing research

Sign up here
Already have an account ?Sign in

Find this document

There are no authors.

Cite this document

Choose a citation style from the tabs below

Save time finding and organizing research with Mendeley

Sign up for free